My Corporis Fabrica Embryo: An ontology-based 3D spatio-temporal modeling of human embryo development

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Article

Pierre-Yves Rabattu, Benoit Massé, Frederico Uliana, Marie-Christine Rousset, Damien Rohmer, Jean-Claude Léon, Olivier Palombi
My Corporis Fabrica Embryo: An ontology-based 3D spatio-temporal modeling of human embryo development
Journal of Biomedical Semantics
2015
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Abstract

In this work, we present a novel ontology describing the development of the human embryology deforming 3D models. Beyond describing how organs and structures are composed, our ontology integrates a procedural description of their 3D representations, temporal deformation and relations with respect to their developments. We also created inferences rules to express complex connections between entities. It results in a unified description of both the knowledge of the organs deformation and their 3D representations enabling to visualize dynamically the embryo deformation during the Carnegie stages. Through a simplified ontology, containing representative entities which are linked to spatial position and temporal process information, we illustrate the added-value of such a declarative approach for interactive simulation and visualization of 3D embryos.